Wikisimpsons - The Simpsons Wiki
In his hallucination, Homer followed the tortoise to a pyramidal structure which then grew to an enormous height, and he had to climb it. At the top of the pyramid, Homer saw a face in the sky appear out of the moon and a planet, and then it manifested as the coyote. The coyote introduced himself as Homer's Spirit Guide, and told Homer to find his soul mate. Shortly after that, Homer woke up.
Homer later heard the voice of the Spirit Guide again, telling him to find his soul mate. When Homer asked for an explanation, the Spirit Guide said that he couldn't tell Homer any new information as he was only his memory.
He was also seen during Chief Wiggum's own chili-induced hallucination. He commented to Wiggle Puppy, Wiggum's spirit guide, about how he had had to help some dumb fat guy. He and Wiggle Puppy then talked briefly, with both agreeing that there should be no more spirit quests until they get a dental plan. He then later went to the spirit guide meeting with Wiggle Puppy.