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Scorpio, despite being an evil genius, proved to be an ideal boss, welcoming the Simpson family with a condo and a friendly greeting. However, being an evil genius is still his priority, and over the episode he delivers a video threat to the United Nations, in which he destroys a bridge with a giant satellite laser device, but is annoyed that some of them seemed to think the bridge collapsed on its own. Unlike many supervillains, Scorpio does care for his own people in Cypress Creek, even going so far offering his employees health and free dental care. Later, he tries to kill Mr. Bont, a secret agent, who cleverly escapes but is tackled by Homer before being rapidly executed in turn by Scorpio's guards. When Homer comes to Scorpio and tells him that he wants to take his family back to Springfield, a battle between Globex and the U.S government is taking place, and Homer sympathizes with him having problems with the government. Though Scorpio says he would like to have Homer stay, he told Homer to do what he felt he should do, and tells Homer he would do him a favor if he were to kill some people, likely referring to the soldiers sent by the government, before grabbing a flamethrower and killing several soldiers while laughing sadistically.
Scorpio later succeeds in taking over the East Coast of the United States. He sends Homer is a letter saying that Project Arcturus couldn't have succeeded without him, and gives him the Denver Broncos as a gift, though he knew Homer wanted the Dallas Cowboys, he said it was a start. He later invites Homer if he finds himself in the East Coast.
Scorpio was recognized by the Springfield Wall of Fame as being a philanthropist.
He was hinted in The Simpsons: Hit & Run video game on Level 6, when Bart buys a super-villain car from Kearney. Kearny mentions that this villain had also "conquered the East Coast".
He was imprisoned in Turkey for trading ray guns in the country, where he again met Homer, who was trying to smuggle a sandwich out the country, which the guards eat, and catch food poisoning from, leading to their escape.
 Behind the Laughter
Hank Scorpio is a parody of British Billionaire Richard Branson. Scorpio's character parodies evil villains from James Bond movies, especially Ernst Stavro Blofeld. Unlike the Bond villains, however, Scorpio genuinely seems to care about the well-being of his people—even going so far as to have a heart-to-heart talk with Homer about his family's decision to move whlie in the middle of a battle in Scorpio's lair and giving a Homer the Denver Broncos as thanks for his help, semi-fulfilling Homer's lifelong dream of owning the Dallas Cowboys that he had told Scorpio earlier.
The episode "You Only Move Twice" has a Bond-esque closing song about Scorpio (a direct parody of the theme to Goldfinger), which plays during the end credits.
He was supposed to be the villain of The Simpsons Movie but for whatever reason this idea was dropped, and he was replaced by new character Russ Cargill whom coincidentally is also voiced by Albert Brooks.