Ginger Flanders is Ned's Vegas wife who he married after getting drunk while on vacation in Las Vegas with Homer.
When Homer and Ned got drunk at Las Vegas, Homer married Amber and Ned married Ginger. Amber and Ginger later dumped them at the desert because they tried to escape.
Ginger and Amber later went to Springfield to stay with their husbands. Ginger escaped because Ned, Rod and Todd were too good (they flushed her cigarettes down the toilet and sang all the day).